Invariant Vα14+NKT Cells Participate in the Early Response to EntericListeria monocytogenesInfection

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Invariant V alpha 14+ NKT cells participate in the early response to enteric Listeria monocytogenes infection.

Invariant Valpha14(+) NKT cells are a specialized CD1-reactive T cell subset implicated in innate and adaptive immunity. We assessed whether Valpha14(+) NKT cells participated in the immune response against enteric Listeria monocytogenes infection in vivo. Using CD1d tetramers loaded with the synthetic lipid alpha-galactosylceramide (CD1d/alphaGC), we found that splenic and hepatic Valpha14(+) ...

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ژورنال

عنوان ژورنال: The Journal of Immunology

سال: 2005

ISSN: 0022-1767,1550-6606

DOI: 10.4049/jimmunol.175.2.1137